Gene expression in different regions of rat tendons submitted to load exercise associated with nandrolone decanoate administration
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چکیده
منابع مشابه
Nandrolone decanoate and load increase remodeling and strength in human supraspinatus bioartificial tendons.
BACKGROUND To date, no studies document the effect of anabolic steroids on rotator cuff tendons. STUDY DESIGN Controlled laboratory study. HYPOTHESIS Anabolic steroids enhance remodeling and improve the biomechanical properties of bioartificially engineered human supraspinatus tendons. METHODS Bioartificial tendons were treated with either nandrolone decanoate (nonload, steroid, n = 18), ...
متن کاملHeart Reaction to Nandrolone Decanoate plus Two Different Intensities of Endurance Exercise: Electrocardiography and Stereological Approach
Background: Regarding the negative effects of androgenic anabolic steroids (AASs) abuse, the long-term effect of nandrolone decanoate with/without two intensities of endurance exercise training was investigated on heart tissue and electrocardiogram (ECG) in rats. Methods: The experiment was conducted on 63 male Wistar rats, which were 4 months old. The rats were divide into groups of control (C...
متن کاملTreatment of aplastic anemia with nandrolone decanoate.
Highly satisfactory results obtained with improvement was seen in two still under 50 mg./week nandrolone decanoate treatment. Once therapy had been com(Deca-Durabolin) for 3-16 months are menced, there was a period of latency reported in 10 cases of aplastic anemia. which fluctuated between 1 and 9 In the series thus treated there were only months. Except for one patient with two deaths, occurr...
متن کاملDecreased Uncoupling Protein 2 and 3 (UCP2 and UCP3) mRNA expression by endurance exercise training with and without chronic administration of nandrolone in rat heart
Introduction: The effect of regular exercise in decreasing the incidence of heart diseases is well known. The abuse of anabolic androgenic steroids (AAS) has been associated with cardiovascular disorders. Uncoupling proteins (UCPs) transport protons across the inner mitochondrial membrane thereby proton gradient can be diminished by the action of UCPs. This process will result in the uncoupl...
متن کاملOverload-induced androgen receptor expression in the aged rat hindlimb receiving nandrolone decanoate.
This study's purpose was to examine whether functional overload with nandrolone decanoate (ND) administration increased muscle mass and steroid receptor concentration in aged rat soleus (Sol) and plantaris (Plan) muscle. ND (6 mg/kg body wt) was administered once a week for 4 wk, whereas control rats received sesame seed oil injections. Functional overload of the hindlimb Sol and Plan was induc...
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2011
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.25.1_supplement.1107.3